FDA & Pediatrics: FDA accepted Shionogi’s sNDA to expand cefiderocol (Fetroja) for pediatric Gram-negative infections, aiming to cover children from birth (≥26 weeks gestational age) through <18 for HABP/VABP and cUTIs, with a PDUFA target of Feb. 23, 2027. Cancer Coverage & Care Delivery: A new look at ctDNA MRD testing in bladder cancer highlights payer coverage gaps (only ~40%–50% coverage), forcing appeals and leaving no standard playbook for surveillance testing frequency and how to manage ctDNA-positive to ctDNA-negative conversions. Pediatric Safety Policy: Pakistan’s Paediatric Association urged DRAP to review a ban on 10cc syringes after pediatric HIV cases in Karachi, arguing the devices are essential for NICUs and children’s care. Allergy & Perioperative Risks: Clinicians warn perioperative anaphylaxis can come from underreported exposures like surgical dyes, latex, and chlorhexidine, complicating workups. Ophthalmology Access: ASRS presentations link loss of retina copay assistance to worse outcomes after switching from branded anti-VEGF to bevacizumab, including more anatomic worsening and shorter injection intervals. Mental Health Tech: A personalized TMS trial in PTSD used fMRI-guided targeting of prefrontal areas connected to the amygdala, showing reduced threat reactivity months later. Healthcare Access in Nigeria: Stakeholders say only 5%–8% of Nigerians have health insurance, urging faster enrollment to prevent families from falling into medical debt.