Medicaid Policy Shock: Advocates say the Trump administration’s Medicaid work requirements are getting tougher than expected, with “medical frailty” exemptions harder to qualify for—raising the risk of large, harmful coverage losses for sick and disabled people. Drug Pricing Fight: Eli Lilly says it will deny 340B discounts to providers that miss documentation requirements next week, while the AHA urges federal action as hospitals warn of added administrative burden and patient harm. Hospital Cost Blueprint: The AHA released a blueprint aimed at lowering healthcare costs and expanding access, targeting admin waste, and drug/device pricing and delivery reforms. AI Cybersecurity Push: A White House executive order directs agencies to harden cybersecurity for AI systems, create an AI cybersecurity clearinghouse, and prioritize enforcement against illegal AI-enabled hacking. Insurance Antitrust Lawsuit: Arizona AG Kris Mayes sued major insurers over alleged price-fixing of provider reimbursements using shared data and an algorithm via MultiPlan. CAR-T Access Logistics: Cencora and Kite agreed to expand US distribution for CAR T therapies, aiming to cut operational friction for community sites. Stroke Trial Update: JAMA reports IV tenecteplase before EVT didn’t improve outcomes for late-window proximal MCA occlusion. Acne OTC Expansion: FDA approved Differin Epiduo Acne Gel for over-the-counter use for ages 12+.